Publications List

Research articles

Ganti KP, Surjit M. 2025. CpG island demethylation and recruitment of SP1 to the promoter region regulates human thymic stromal lymphopoietin expression. Epigenetics, 20 (1), 2529358.

Ansari S, Sarmah DT, Verma R, Chandrasekar K, Shalimar, Nayak B, Chatterjee S, Surjit M. 2025. Network controllability analysis reveals the antiviral potential of Etravirine against Hepatitis E Virus infection. mSystems, e00438-25.

Gupta P, Khadake RM, Singh ON, Mirgane HA, Gupta D, Bhosale SV, Vrati S, Surjit M, Rode AB. 2025. Targeting Two-Tetrad RNA G-Quadruplex in the SARS-CoV-2 RNA Genome Using Tetraphenylethene Derivatives for Antiviral Therapy. ACS Infect Dis. 11(3):784-795.

Ansari S, Gupta N, Verma R, Singh ON, Gupta J, Kumar A, Yadav MK, Binayke A, Tiwari M, Periwal N, Sood V,Mani S, Awasthi A, Shalimar, Nayak B, Ranjith-Kumar CT, Surjit M. 2023. Antiviral activity of the Human endogenous retrovirus-R Envelope protein against the severe acute respiratory syndrome-coronavirus-2. EMBO reports. 2023, e55900, 10.15252/embr.202255900.

Kumar S, Verma R, Saha S, Agrahari A, Shukla S, Singh O.N., Berry U, Anurag, Maiti T.K., Asthana S, Ranjith-Kumar C.T, Surjit M. 2023. RNA-protein interactome at the Hepatitis E virus internal ribosome entry site. Microbiology Spectrum, 2023, 10.1128/spectrum.02827-22.

Kumar A, Subramani C, Raj S, Ranjith-Kumar CT, Surjit M. 2023. Hepatitis E Virus Protease Inhibits the Activity of Eukaryotic Initiation Factor 2-Alpha Kinase 4 and Promotes Virus Survival. Journal of Virology, 2023, 10.1128/jvi.00347-23.

Agarwal S, Kaur S, Asuru TR, Joshi G, Shrimali NM, Singh A, Singh ON, Srivastva P, Shrivastava T, Vrati S, Surjit M, Guchhait P. 2022. Dietary alpha-ketoglutarate inhibits SARS CoV-2 infection and rescues inflamed lungs to restore O2 saturation by inhibiting pAkt. Clin Transl Med. 12(9):e1041.

Gupta J, Irfan M, Ramgir N, Muthe KP, Debnath AK, Ansari S, Gandhi J, Ranjith-Kumar CT, Surjit M. 2022. Antiviral Activity of Zinc Oxide Nanoparticles and Tetrapods Against the Hepatitis E and Hepatitis C Viruses. Front Microbiol. 13:881595.

Saha S, Verma R, Kumar C, Kumar B, Dey AK, Surjit M, Mylavarapu SVS, Maiti TK. 2022. Proteomic analysis reveals USP7 as a novel regulator of palmitic acid-induced hepatocellular carcinoma cell death. Cell Death Dis.13(6):563.

Tripathi A, Singh Rawat B, Addya S, Surjit M, Tailor P, Vrati S, Banerjee A. 2021. Lack of Interferon (IFN) Regulatory Factor 8 Associated with Restricted IFN-γ Response Augmented Japanese Encephalitis Virus Replication in the Mouse Brain. J Virol. 95(21):e0040621.

Rizvi ZA, Tripathy MR, Sharma N, Goswami S, Srikanth N, Sastry JLN, Mani S, Surjit M, Awasthi A, Dikshit M. 2021. Effect of Prophylactic Use of Intranasal Oil Formulations in the Hamster Model of COVID-19. Front Pharmacol. 12:746729.

Verma, R, Saha S, Kumar S, Mani S, Maiti TK, Surjit M. 2021. RNA-protein interaction analysis of SARS-CoV-2 5’- and 3’-untranslated regions reveal a role of lysosome-associated membrane protein-2a during viral infection. mSystems 6, e00643-21.

Shrivastava T, Singh B, Rizvi ZA, Verma R, Goswami S, Vishwakarma P, Jakhar K, Sonar S, Mani S, Bhattacharyya S, Awasthi A, Surjit M. 2021. Comparative Immunomodulatory Evaluation of the Receptor Binding Domain of the SARS-CoV-2 Spike Protein; a Potential Vaccine Candidate Which Imparts Potent Humoral and Th1 Type Immune Response in a Mouse Model. Front Immunol. 12:641447.

Kao C, Surjit M, Ranjith-Kumar CT. Editorial: Viral Hepatitis: Pathophysiology, prevention and control. 2021. Front Cell and Infect Microbiol.

Sehrawat, S, Khasa R, Deb A, Prajapat SK, Mallick S, Basu A, Surjit M, Kalia M, Vrati S. 2021. Valosin-containing protein/p97 plays critical roles in the Japanese encephalitis virus life cycle. Journal of Virology 95, 11.

Majumdar S, Verma R, Saha A, Bhattacharyya P, Maji P, Surjit M, Kundu M, Basu J, Saha S. 2020. Perspectives about modulating host immune system in targeting SARS-CoV-2 in India. Frontiers in genetics 12, 125.

Mittal A, Gupta A, Kumar S, Surjit M, Singh B, Soneja M, Soni KD, Khan AR, Singh K, Naik S, Kumar A. 2020. Gargle lavage as a viable alternative to swab for detection of SARS-CoV-2. Indian Journal of Medical Research152(1), 77.

Hingane S, Joshi N, Surjit M, Ranjith-Kumar CT. 2020. Hepatitis E virus ORF2 inhibits RIG-I mediated interferon response. Front Microbiol. 15, 656.

Gupta J, Kaul S, Srivastava A, Kaushik N, Ghosh S, Sharma C, Batra G, Banerjee M, Shalimar, Nayak B, Ranjith-Kumar CT, Surjit M. 2020. Expression, Purification and Characterization of the Hepatitis E Virus Like-Particles in the Pichia pastoris. Front Microbiol. 11:141.

Anang S, Kaushik N, Hingane S, Kumari A, Gupta G, Asthana S, Shalimar, Nayak B, Ranjith-Kumar CT, Surjit M. 2018. Potent inhibition of hepatitis E virus release by a cyclic peptide inhibitor of the interaction between viral open reading frame 3 protein and host tumor susceptibility gene 101. J Virol, DOI: 10.1128/JVI.00684-18.

Chandru S, Nair V, Anang S, Mandal SD, Pareek M, Kaushik N, Srivastava A, Saha S, Shalimar, Nayak B, Ranjith-Kumar CT, Surjit M. 2018. Host-virus protein interaction network reveals the involvement of multiple host processes in the life cycle of hepatitis E virus. mSystems. 3, e00135-17.

Kaushik N, Subramani C, Anang S, Muthumohan R, Shalimar, Nayak B, Ranjith-Kumar CT, Surjit M. 2017. Zinc Salts Block Hepatitis E Virus Replication by Inhibiting the Activity of Viral RNA-Dependent RNA Polymerase. J Virol. 91, 00754-17.

Madhvi A, Hingane S, Srivastav R, Joshi N, Subramani C, Muthumohan R, Khasa R, Varshney S, Kalia M, Vrati S, Surjit M, Ranjith-Kumar CT. 2017. A screen for novel hepatitis C virus RdRp inhibitor identifies a broad-spectrum antiviral compound. Sci Rep. 7, 5816.

Ganti KP, Mukherji A, Surjit M, Li M, Chambon P. 2017. Similarities and differences in the transcriptional control of expression of the mouse TSLP gene in skin epidermis and intestinal epithelium. Proc Natl Acad Sci U S A. 114, E951E960.

Nair VP and Surjit M. 2017. RNA Strand Displacement Assay for Hepatitis E Virus Helicase. Bio-protocol. 7, e2198.

Nair VP, Anang S, Srivastava A, Surjit M. 2017. RNA-dependent RNA Polymerase Assay for Hepatitis E Virus. Bio-protocol. 7, e2199.

Wang W, Hakim MS, Nair VP, de Ruiter PE, Huang F, Sprengers D, Van Der Laan LJ, Peppelenbosch MP, Surjit M, Pan Q. 2016. Distinct Antiviral Potency of Sofosbuvir Against Hepatitis C and E Viruses. Gastroenterology. 151, 12511253.

Nair VP, Anang S, Subramani C, Madhvi A, Bakshi K, Srivastava A, Shalimar, Nayak B, Ct RK, Surjit M. 2016. Endoplasmic Reticulum Stress Induced Synthesis of a Novel Viral Factor Mediates Efficient Replication of Genotype-1 Hepatitis E Virus. PLoS Pathogens, 12, e1005521.

Anang S, Subramani C, Nair VP, Kaul S, Kaushik N, Sharma C, Tiwari A, Ranjith-Kumar CT, Surjit M. 2016. Identification of critical residues in Hepatitis E virus macro domain involved in its interaction with viral methyltransferase and ORF3 proteins. Sci Rep. 6, 25133.

Surjit M, Varshney B, Lal SK. 2012. The ORF2 glycoprotein of Hepatitis E Virus inhibits cellular NF-kB activity by blocking ubiquitination mediated proteasomal degradation of IκBα in human hepatoma cells. BMC Biochemistry. 13, 7.

Surjit M, Ganti KP ∗, Mukherji A ∗, Tao Y, Hua G, Metzger D, Li M, Chambon P. 2011. Widespread negative response elements mediate direct repression by agonist-liganded glucocorticoid receptor. Cell. 145, 224-241.

Surjit M, Jameel S, Lal SK. 2007. Cytoplasmic localization of the ORF2 protein of hepatitis E virus is dependent on its ability to undergo retrotranslocation from the endoplasmic reticulum. J Virol. 81, 3339-3345.

Surjit M, Lal SK. 2007. Glycogen synthase kinase-3 phosphorylates and regulates the stability of p27kip1 protein. Cell Cycle. 6, 580-588.

Sharma K, Surjit M, Satija N, Liu B, Chow VT, Lal SK. 2007. The 3a accessory protein of SARS coronavirus specifically interacts with the 5'UTR of its genomic RNA, Using a unique 75 amino acid interaction domain. Biochemistry. 46, 64886499.

Surjit M, Liu B, Chow VT, Lal SK. 2006. The nucleocapsid protein of severe acute respiratory syndrome-coronavirus inhibits the activity of cyclin-cyclindependent kinase complex and blocks S phase progression in mammalian cells. J Biol Chem. 281, 10669-10681.

Surjit M, Oberoi R, Kumar R, Lal SK. 2006. Enhanced alpha1 microglobulin secretion from Hepatitis E virus ORF3-expressing human hepatoma cells is mediated by the tumor susceptibility gene 101. J Biol Chem. 281, 8135-8142.

Surjit M, Kumar R, Mishra RN, Reddy MK, Chow VT, Lal SK. 2005. The SARS coronavirus nucleocapsid (N) protein is phosphorylated and localizes in the cytoplasm by 14-3-3 mediated translocation. J Virol. 79,11476-11486.

Tyagi S, Surjit M, Lal SK. 2005. The ORF3 protein of Hepatitis E Virus interacts with Bikunin, a Kunitz-type serine protease inhibitor, using its 41 amino acid C-terminal region. J Virol. 79, 12081-12087.

Tyagi S, Surjit M, Roy AK, Jameel S, Lal SK. 2004. The ORF3 protein of hepatitis E virus interacts with liver-specific alpha1-microglobulin and its precursor alpha1-microglobulin/bikunin precursor (AMBP) and expedites their export from the hepatocyte. J Biol Chem. 279, 29308-29319.

Surjit M, Jameel S, Lal SK. 2004. The ORF2 protein of hepatitis E virus binds the 5' region of viral RNA. J Virol. 78, 320-328.

Surjit M, Liu B, Jameel S, Chow VT, Lal SK. 2004. The SARS coronavirus nucleocapsid protein induces actin reorganization and apoptosis in COS-1 cells in the absence of growth factors. Biochem J. 383, 8-13.

Surjit M, Liu B, Kumar P, Chow VT, Lal SK. 2004. The nucleocapsid protein of the SARS coronavirus is capable of self-association through a C-terminal 209 amino acid interaction domain. Biochem Biophys Res Commun. 317, 10301036.

Review articles

Ghosh S, Kumar S, Verma R, Ansari S, Chatterjee S, Surjit M. 2025. Emerging RNA-centric technologies to probe RNA-protein interactions: importance in decoding the life cycle of positive sense single strand RNA viruses and antiviral discovery. Front Cel Infect Microbiol. 15:1580337.

Kumar S, Ansari S, Narayanan S, Ranjith-Kumar CT, Surjit M. 2023. Antiviral activity of Zinc against hepatitis viruses: current status and future prospects. Front Microbiol. 14, DOI: 10.3389/fmicb.2023.1218654.

Kaushik N, Anang S, Ganti KP, Surjit M. 2018. Zinc: A potential antiviral against hepatitis E virus infection? DNA and Cell Biol. 37, 593-599.

Anang S, Kaushik N, Surjit M. 2018. Recent advances towards the development of a potent antiviral against the Hepatitis E virus. J Clin Trans Hepatol. 6, 1-7.

Surjit M, Lal SK. 2008. The SARS-CoV nucleocapsid protein: a protein with multifarious activities. Infect Genet Evol. 4, 397-405.

Book chapters

R Verma, S Raj, U Berry, CT Ranjith-Kumar, Milan Surjit. 2022. Drug repurposing for COVID-19 therapy: Pipeline, current status and challenges. Drug Repurposing for Emerging Infectious Diseases and Cancer (ed. Sunil Lal and R. C. Sobti) Springer, Germany.

Gupta J, Kumar A, Surjit M. 2022. Production of a Hepatitis E Vaccine Candidate Using the Pichia pastoris Expression System. Methods Mol Biol. 2412:117-141.

R Verma, R Kaur, S K Lal, M Surjit. 2021. Insight into molecular evolution and increased transmissibility of the Severe Acute Respiratory Syndrome-Coronavirus-2. Uncovering the Science of COVID-19 (ed. VTK Chow and S K Lal) World Scientific Publishing Co. India.

M. Surjit and S. K. Lal. 2010. ORF3 protein of Hepatitis E virus: possible structural and regulatory functions during viral pathogenesis. (eds. D. Raghunath & V. Nagaraja) Mechanisms of Microbial Pathogenesis. Macmillan, Bangalore. p 168-182.

M. Surjit and S. K. Lal. 2010. The nucleocapsid protein of the SARS Coronavirus: Structure, Function and Therapeutic potential. (ed. S. K. Lal) Molecular Biology of the SARS-Coronavirus. Springer. Germany. p129-151.

M. Surjit, Bhavna Varshney and S. K. Lal. 2006. Molecular biology of the Severe Acute respiratory Syndrome (SARS) Coronavirus. (ed. T. Mizutani) Molecular Biology of the SARS-Coronavirus. Transworld Research Network, India. p1-16.